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You are a disease. Infect the human body as a lone pathogen in this cellular roguelike shooter.
93%of 4,216 Steam reviews— Very Positive93% of 4,216 Steam reviews are positive — Very Positive
Creators who played it
Matched to this game by title, from YouTube. Not an endorsement, and not a ranking.
In Pathogenic, you are the disease. Experience a visceral 2D roguelike twin-stick shooter where you play as a lone parasite fighting a desperate war against the immune system. Your goal is simple: infect and conquer your human host.
To survive, you must adapt. Hunt down enemy cells, rip out their organelles, and graft them onto your own body. Evolve from a simple cell into a complex engine of destruction. Create powerful, game-breaking builds and become the ultimate pathogen.
Loot, graft, and assemble your parasite from dozens of unique organelles. Combine flagella for movement, mitochondria for power, secretors for ranged attacks, and spikes for melee combat. Chain organelle effects and discover powerful synergies to build an unstoppable disease vector.
Battle a diverse roster of enemies, from basic immune cells like macrophages and T cells to rival parasites such as tapeworms or protozoa. Formidable bosses are lurking deep within the host's organs.
Collect plasmid fragments to permanently upgrade your parasite's plasmid tree between runs. Each parasite will have it's own upgrade tree allowing for a range of builds to suit your preferred playstyle.
Navigate the procedurally generated organic landscape of the human body. Travel through distinct biomes like the branching pathways of the lungs, the pulsating chambers of the heart, and the complex neural network of the brain.
Our detailed, colorful world is powered by a soft-body physics simulation, giving every cell, enemy, and projectile a uniquely satisfying organic feel. The combination of hand-crafted design and procedural generation ensures endless variety - each run offers a fresh and challenging gameplay experience.
End of the developer's description of Pathogenic.Matched to this game by title, from YouTube. Not an endorsement by the creators, and not a ranking.
Ranked by shared tags, then by score.
I'm No Demonlord
Don't miss the latest updates on [Discord / YouTube / X]! Follow and add us—we’re waiting for you! Check out the community information on the right! Once upon a time, a legendary archmage sacrificed himself to cast a magical seal on a supervillain, allowing the kingdom to prosper. But when the king began arresting commoners without reason, the vanished people were never seen again. One
RAZE
«RAZE» is an action roguelike where everything revolves around randomness. You play as a fearless cat warrior, one of the guardians of the Shadow World and a member of the legendary feline unit «BLACKWATCH». Your main goal is to stop the evil that was born in your dimension before everything spirals out of control. One of the gods of the Shadow World steals an ancient and powerful artifact
Underwater DuO
Control the turtle with your left hand and smash everything in your path! Control the jellyfish with your right hand and blast your enemies! How long can you survive? Underwater Duo is a charming top-down action shooter where two inseparable aquatic partners venture into an unknown sea. Facing waves of hostile underwater creatures, they must rely on exceptional coordination and strength to c
You are a disease. Infect the human body as a lone pathogen in this cellular roguelike shooter.
93%of 4,216 Steam reviews— Very Positive93% of 4,216 Steam reviews are positive — Very Positive
Creators who played it
Matched to this game by title, from YouTube. Not an endorsement, and not a ranking.
In Pathogenic, you are the disease. Experience a visceral 2D roguelike twin-stick shooter where you play as a lone parasite fighting a desperate war against the immune system. Your goal is simple: infect and conquer your human host.
To survive, you must adapt. Hunt down enemy cells, rip out their organelles, and graft them onto your own body. Evolve from a simple cell into a complex engine of destruction. Create powerful, game-breaking builds and become the ultimate pathogen.
Loot, graft, and assemble your parasite from dozens of unique organelles. Combine flagella for movement, mitochondria for power, secretors for ranged attacks, and spikes for melee combat. Chain organelle effects and discover powerful synergies to build an unstoppable disease vector.
Battle a diverse roster of enemies, from basic immune cells like macrophages and T cells to rival parasites such as tapeworms or protozoa. Formidable bosses are lurking deep within the host's organs.
Collect plasmid fragments to permanently upgrade your parasite's plasmid tree between runs. Each parasite will have it's own upgrade tree allowing for a range of builds to suit your preferred playstyle.
Navigate the procedurally generated organic landscape of the human body. Travel through distinct biomes like the branching pathways of the lungs, the pulsating chambers of the heart, and the complex neural network of the brain.
Our detailed, colorful world is powered by a soft-body physics simulation, giving every cell, enemy, and projectile a uniquely satisfying organic feel. The combination of hand-crafted design and procedural generation ensures endless variety - each run offers a fresh and challenging gameplay experience.
End of the developer's description of Pathogenic.Matched to this game by title, from YouTube. Not an endorsement by the creators, and not a ranking.
Ranked by shared tags, then by score.
I'm No Demonlord
Don't miss the latest updates on [Discord / YouTube / X]! Follow and add us—we’re waiting for you! Check out the community information on the right! Once upon a time, a legendary archmage sacrificed himself to cast a magical seal on a supervillain, allowing the kingdom to prosper. But when the king began arresting commoners without reason, the vanished people were never seen again. One
RAZE
«RAZE» is an action roguelike where everything revolves around randomness. You play as a fearless cat warrior, one of the guardians of the Shadow World and a member of the legendary feline unit «BLACKWATCH». Your main goal is to stop the evil that was born in your dimension before everything spirals out of control. One of the gods of the Shadow World steals an ancient and powerful artifact
Underwater DuO
Control the turtle with your left hand and smash everything in your path! Control the jellyfish with your right hand and blast your enemies! How long can you survive? Underwater Duo is a charming top-down action shooter where two inseparable aquatic partners venture into an unknown sea. Facing waves of hostile underwater creatures, they must rely on exceptional coordination and strength to c
I'm No Demonlord
Don't miss the latest updates on [Discord / YouTube / X]! Follow and add us—we’re waiting for you! Check out the community information on the right! Once upon a time, a legendary archmage sacrificed himself to cast a magical seal on a supervillain, allowing the kingdom to prosper. But when the king began arresting commoners without reason, the vanished people were never seen again. One
I'm No Demonlord
Don't miss the latest updates on [Discord / YouTube / X]! Follow and add us—we’re waiting for you! Check out the community information on the right! Once upon a time, a legendary archmage sacrificed himself to cast a magical seal on a supervillain, allowing the kingdom to prosper. But when the king began arresting commoners without reason, the vanished people were never seen again. One